Yitzhak Apeloig is a chemist, a member of the Schulich Faculty of Chemistry at the Technion. During World War II his family escaped from Poland and settled in Bukhara, where Yitzhak was born. In 1947, when he was a toddler, his family immigrated to the Land of Israel. He earned all his academic degrees at the Hebrew University of Jerusalem: a bachelor’s degree in physics and chemistry, a master’s degree in chemistry, and a doctorate in chemistry. He joined the Technion’s academic staff in 1976. His main contribution is the introduction of computational chemistry and the use of theoretical calculations to predict the properties of materials containing silicon that were unknown and in proposing ways to prepare them. He is a pioneer in the use of calculations based on quantum mechanics for predicting the physical and chemical properties of materials. During his tenure as president of the Technion, Israeli high tech industry, in which Technion graduates constitute an impressive majority, expanded greatly and two Technion researchers, Aaron Ciechanover and Avram Hershko, won the Nobel Prize. As a researcher, Apeloig has been awarded some of the highest scientific prizes awarded to scientists, including the Frederick Stanley Kipping Award in Silicon Chemistry from the American Chemical Society. He was elected to the American Academy of Arts and Sciences, he was awarded the 2021 Schrödinger Medal by the World Association of Theoretical and Computational Chemists, and the journal Chemistry dedicated an issue to Apeloig on the occasion of his 65th birthday.